Study of gastrointestinal stromal tumors with c-kit immunostaining
نویسندگان
چکیده
منابع مشابه
C-kit gene mutation in human gastrointestinal stromal tumors.
AIM To investigate the significance of c-kit gene mutation in gastrointestinal stromal tumors (GIST). METHODS Fifty two cases of GIST and 28 cases of other tumors were examined. DNA samples were extracted from paraffin sections and fresh blocks. Exons 11, 9 and 13 of the c-kit gene were amplified by PCR and sequenced. RESULTS Mutations of exon 11 were found in 14 of 25 malignant GISTs (56%)...
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ژورنال
عنوان ژورنال: Journal of Pathology of Nepal
سال: 1970
ISSN: 2091-0908,2091-0797
DOI: 10.3126/jpn.v1i1.4450